Adverse reactions reported in post-marketing studies and not observed in placebo-controlled clinical trials. In patients who received viagra® 1 time per day, there was a slightly higher frequency of recorded ECG changes, primarily sinus bradycardia, compared with placebo. Most of the ECG abnormalities were not associated with adverse reactions.
There are limited data on the reactions of patients over 65 years of age who received viagra® for the treatment of erectile dysfunction or benign prostatic hyperplasia in clinical trials. In clinical studies, when taking 5 mg of the drug once a day for the treatment of benign prostatic hyperplasia, dizziness and diarrhea were noted with a greater frequency in patients over 75 years old.
The presence of contraindications to sexual activity in patients with diseases of the cardiovascular system: myocardial infarction within the last 90 days, unstable angina pectoris, the occurrence of an attack of angina pectoris during intercourse, heart failure classes II-IV according to the classification of the New York Heart Association (NYHA), developed within the last 6 months, uncontrolled arrhythmia, arterial hypotension (blood pressure less than 90/50 mm Hg), uncontrolled arterial hypertensionzia, ischemic stroke within the last 6 months.